Anxiety & Panic Disorder
Symptoms, Causes & Treatment
Everything you need to know about anxiety and panic disorder: what causes them, how they are diagnosed, and the effective treatments available.
What Are Anxiety & Panic Disorder?
Anxiety is the most common mental health condition in the UK, affecting an estimated 8 million people at any given time. While anxiety is a normal and adaptive emotional response to perceived threat or uncertainty – serving an important evolutionary function in alerting us to danger and preparing the body to respond – it becomes a clinical disorder when it is excessive, persistent, difficult to control, and causes significant distress or impairment in daily life.
Anxiety disorders are a family of related but distinct conditions, each with characteristic features. The most prevalent include:
Generalised Anxiety Disorder (GAD) – characterised by persistent, excessive worry about a wide range of everyday matters (health, finances, work, relationships) that is difficult to control and is present on most days. GAD affects approximately 5% of the UK population and is often accompanied by physical symptoms such as muscle tension, fatigue, and sleep disturbance.
Panic Disorder – characterised by recurrent unexpected panic attacks – intense episodes of severe fear accompanied by physical symptoms (such as racing heart, chest tightness, and breathlessness) that reach a peak within minutes. Panic disorder is often accompanied by persistent worry about having further attacks and avoidance of situations perceived as likely to trigger them.
Social Anxiety Disorder (Social Phobia) – intense fear of social or performance situations in which the person fears they will act in a way that will be humiliating or embarrassing. Social anxiety significantly restricts social and professional functioning.
Health Anxiety (Illness Anxiety Disorder) – excessive and persistent preoccupation with the possibility of having a serious illness, despite medical reassurance.
Specific Phobias – intense, irrational fear of specific objects or situations (spiders, heights, flying, needles, etc.) that leads to avoidance.
Agoraphobia – fear and avoidance of situations in which escape might be difficult or help unavailable in the event of a panic attack; frequently develops in association with panic disorder.
Anxiety disorders are highly treatable. The majority of people who receive appropriate treatment achieve significant or full remission of symptoms.
What Are the Symptoms of Anxiety & Panic Disorder?
Anxiety disorders produce both psychological and physical symptoms. The pattern differs between Generalised Anxiety Disorder and Panic Disorder, though there is often significant overlap.
- Persistent, excessive worry about multiple areas of life (work, health, finances, relationships)
- Feeling on edge, restless, or wound up
- Difficulty concentrating or mind going blank
- Irritability
- Muscle tension or aches
- Sleep disturbance — difficulty falling or staying asleep
- Fatigue from constant state of alertness
- Physical symptoms: headaches, stomach upset, sweating
- Sudden, intense surge of fear or discomfort peaking within minutes
- Pounding or racing heart (palpitations)
- Shortness of breath or feeling of choking
- Chest pain or tightness
- Dizziness, lightheadedness, or feeling faint
- Tingling or numbness in the hands or face
- Sweating, trembling, or shaking
- Feeling of unreality or detachment (derealisation)
- Fear of losing control, going mad, or dying
- Persistent worry about future attacks and avoidance of situations where attacks have occurred
If anxiety is accompanied by thoughts of suicide or self-harm, seek immediate help. Call 999 or go to A&E if you are in immediate danger. The Samaritans are available 24 hours a day on 116 123. If you experience sudden severe chest pain, difficulty breathing, or other symptoms you cannot distinguish from a cardiac emergency, call 999 immediately — a clinician can assess whether it is a panic attack or something else.
What Causes Anxiety & Panic Disorder?
Anxiety disorders arise from a combination of biological vulnerability, psychological factors, and environmental triggers. Understanding what is driving your anxiety is an important part of finding the right treatment.
Anxiety disorders involve dysregulation of the brain’s threat-detection system, particularly the amygdala. Overactivation of the fight-or-flight response — mediated by adrenaline and cortisol — produces the physical and psychological symptoms of anxiety even in the absence of genuine danger.
Anxiety disorders run in families, suggesting a significant genetic component. Twin studies indicate that genes account for approximately 30–40% of the risk. However, having a genetic predisposition does not mean anxiety is inevitable — environmental factors are equally important.
Stressful or traumatic life events — including accidents, abuse, bereavement, relationship difficulties, or work pressure — can trigger anxiety disorders. Early adverse experiences in childhood are a particularly strong risk factor for later anxiety.
Excessive caffeine, alcohol dependency, recreational drug use, and withdrawal from certain substances (including alcohol and benzodiazepines) can all trigger or significantly worsen anxiety symptoms. Stimulants in particular can precipitate panic attacks.
Certain medical conditions — including hyperthyroidism, cardiac arrhythmias, hypoglycaemia, and anaemia — can produce symptoms that closely mimic anxiety or panic. These must be excluded at assessment, particularly when anxiety presents without a clear psychological trigger.
Learned patterns of avoidance, negative thinking styles (catastrophising, overestimating threat), and poor distress tolerance all maintain and perpetuate anxiety over time. Avoiding feared situations provides short-term relief but reinforces anxiety in the long run.
Key Risk Factors
How Is Anxiety & Panic Disorder Diagnosed?
Anxiety disorders are diagnosed clinically through a structured interview and validated questionnaires. A clinician will explore the nature, duration, and impact of your symptoms, assess for comorbid conditions, and arrange blood tests to rule out medical causes where appropriate. There is no single test for anxiety — diagnosis is based on your symptom pattern and its effect on your daily life.
How Are Anxiety & Panic Disorder Treated?
Anxiety disorders are highly treatable. NICE guidelines recommend a stepped-care approach, starting with self-help and low-intensity interventions for mild symptoms, and escalating to CBT, medication, or a combination for moderate to severe presentations. Most people with anxiety disorders who receive appropriate treatment experience significant improvement.
Supportive Measures
Alongside formal treatment, day-to-day management of anxiety is significantly improved by consistent lifestyle practices. Regular exercise, adequate sleep, reducing caffeine and alcohol, and maintaining social connections all reduce baseline anxiety levels. Controlled breathing techniques — particularly slow, diaphragmatic breathing with a prolonged exhalation — can reduce acute anxiety and panic symptoms within minutes. Keeping a worry journal to externalise anxious thoughts, and scheduling dedicated ‘worry time’ to contain rumination, are simple but effective CBT-derived strategies.
Chronic & Treatment-Resistant Anxiety
Without treatment, anxiety disorders tend to be chronic and relapsing. Many people experience multiple episodes across their lifetime. Treatment-resistant anxiety — where symptoms persist despite adequate trials of CBT and two or more medications — may require specialist assessment. Options include augmentation strategies, different classes of medication, intensive therapy formats, or referral to a specialist anxiety clinic. Comorbid conditions such as depression, OCD, or PTSD should also be identified and treated, as they can perpetuate anxiety if left unaddressed.
When Should You Seek Medical Advice for Anxiety?
You are experiencing chest pain, severe difficulty breathing, or other symptoms you cannot distinguish from a cardiac emergency · Anxiety is accompanied by thoughts of suicide or self-harm · You are unable to care for yourself or dependants due to the severity of symptoms · There is a sudden onset of severe psychological distress with confusion or disorientation.
Anxiety or panic symptoms are new, worsening, or significantly affecting your ability to work or manage daily life · You are avoiding increasing numbers of situations because of anxiety · You are using alcohol or substances to manage anxiety · You suspect a medical cause for your symptoms · A current medication is not working or is causing side effects · You have anxiety alongside low mood or thoughts of self-harm.
How Can You Reduce Your Risk of Anxiety?
While anxiety disorders cannot always be prevented, particularly where there is a strong genetic component, a number of evidence-based habits significantly reduce vulnerability to anxiety and support long-term mental wellbeing.
Mindfulness-based practices — including meditation, breathing exercises, and body scanning — reduce the physiological stress response and train the brain to observe anxious thoughts without reacting to them. Even ten minutes a day has measurable benefits for anxiety.
Regular physical activity reduces cortisol and adrenaline levels, releases endorphins, and improves sleep — all of which reduce anxiety. Aerobic exercise three to five times per week is particularly effective for both GAD and panic disorder.
Caffeine stimulates the central nervous system and can directly trigger or worsen anxiety and panic attacks. Reducing or eliminating caffeine — and limiting alcohol, which disrupts sleep and worsens mood — can produce rapid improvements in anxiety levels.
Poor sleep increases anxiety sensitivity and makes worry harder to control. Maintaining a consistent sleep schedule, creating a wind-down routine, and avoiding screens and stimulants before bed all significantly improve sleep quality and anxiety resilience.
Learning to recognise catastrophic thinking patterns — such as overestimating threat or assuming the worst outcome — and actively challenging them is a core CBT skill that can be practised independently between therapy sessions or through self-help resources.
Maintaining regular contact with trusted friends and family provides emotional support and perspective. Sharing concerns with others — rather than internalising worry — reduces the cognitive burden of anxiety and counters the isolation that can reinforce it.
Speak to a Clinician About Anxiety and Panic Disorder
Living with anxiety or panic disorder does not have to be the norm. Through The GP Service, you can speak to a licensed clinician in a private, confidential online consultation — from home, at a time that suits you. A clinician can assess your symptoms, discuss your treatment options, and refer you for talking therapy or prescribe medication where appropriate.



Expert clinical advice, when you need it.
Anxiety & Panic Disorder FAQs
Anxiety becomes a disorder when it is excessive, persistent, difficult to control, and causes significant distress or impairment in daily functioning. Normal anxiety is a proportionate, temporary response to a genuine threat — for example, feeling nervous before an exam or a job interview. Anxiety disorder involves worry or fear that is out of proportion to the situation, occurs across multiple areas of life, and persists even when there is no immediate stressor. If anxiety is affecting your ability to work, maintain relationships, or enjoy daily life, it warrants clinical assessment.
A panic attack is a sudden, intense episode of fear accompanied by physical symptoms including palpitations, shortness of breath, chest tightness, dizziness, and a sense of impending doom. Attacks typically peak within ten minutes and resolve within twenty to thirty minutes. Although extremely frightening, panic attacks are not physically dangerous. The physical symptoms are caused by the body’s adrenaline response, not by a heart attack or other medical emergency. Panic disorder is diagnosed when attacks are recurrent and lead to persistent worry about future attacks and avoidance behaviour.
The most effective treatments for anxiety disorders are Cognitive Behavioural Therapy (CBT) and medication — most commonly SSRIs such as sertraline or escitalopram. For mild to moderate anxiety, guided self-help and CBT alone are often sufficient. For moderate to severe anxiety, medication combined with therapy produces the best outcomes. NICE recommends a stepped-care approach — starting with the least intensive effective intervention and stepping up if needed. A clinician can help you decide which approach is right for your situation.
Breathing exercises work by activating the parasympathetic nervous system — the body’s ‘rest and digest’ response — which counteracts the adrenaline-driven fight-or-flight response underlying anxiety and panic. The most evidence-based technique is slow diaphragmatic breathing: inhale for four counts, hold for one, exhale slowly for six counts. Practising this regularly — not just during anxiety — trains the nervous system to regulate more effectively. During a panic attack, focusing on slow exhalation can reduce symptom intensity within minutes.
SSRIs are not addictive in the conventional sense — they do not cause tolerance or cravings. However, stopping them too quickly can cause discontinuation symptoms, which is why they should always be tapered gradually under clinical supervision. Benzodiazepines (such as diazepam) are different — they carry a significant risk of dependence and are no longer recommended for long-term treatment of anxiety disorders. If you have been prescribed a benzodiazepine and are concerned, speak to your clinician about a supervised reduction plan.
GAD and panic disorder frequently co-occur with depression, and the two conditions share overlapping neurobiological and psychological mechanisms. Around 50% of people with GAD also meet criteria for depression. When both conditions are present, treatment typically targets both simultaneously — SSRIs are effective for both, and CBT can be adapted to address the interplay between low mood and anxiety. It is important to tell your clinician about all your symptoms so that both conditions can be appropriately addressed.
CBT for anxiety and panic disorder typically involves psychoeducation about anxiety, identifying and challenging distorted thinking patterns (cognitive restructuring), gradual exposure to feared situations or sensations (exposure therapy), and building a toolkit of coping strategies. For panic disorder, interoceptive exposure — deliberately inducing the physical sensations of panic in a controlled way — is a key component. NICE recommends 12–20 sessions for anxiety disorders; shorter high-intensity CBT or guided self-help may be sufficient for milder presentations.
Many people with anxiety also experience OCD (Obsessive-Compulsive Disorder), PTSD (Post-Traumatic Stress Disorder), social anxiety disorder, specific phobias, or health anxiety. These are distinct conditions with shared anxiety features but different treatment approaches. A thorough clinical assessment will identify the primary diagnosis and any coexisting conditions, ensuring that treatment is appropriately targeted. If you think you might have one of these conditions, raising it with your clinician is an important first step.
