Joint Pain
Symptoms, Causes & Treatment
Understanding joint pain: how to tell the difference between OA, RA, gout, and other causes, what investigations are needed, and the treatments that work.
What Is Joint Pain?
Joint pain (arthralgia) is one of the most common reasons for consulting a GP. It ranges from a single painful joint after an injury to widespread arthritis affecting multiple joints. The pattern of involvement — which joints are affected, whether the onset was sudden or gradual, and the presence of systemic features — guides the diagnosis.
The most important distinction is between non-inflammatory joint pain (OA, injury) and inflammatory joint pain (RA, gout, psoriatic arthritis). Inflammatory arthritis requires prompt diagnosis and DMARD treatment to prevent irreversible joint damage.
A hot, red, severely swollen single joint with fever must be treated as septic arthritis until proved otherwise. This is a surgical emergency.
What Are the Symptoms of Joint Pain?
The character, pattern, and associated features of joint pain guide the differential diagnosis and investigation pathway.
Joint pain, swelling, or stiffness · Warmth and redness over joint · Reduced range of movement · Crepitus (grinding or clicking sounds) · Joint deformity · Fatigue and systemic symptoms in inflammatory arthritis
Sudden, hot, red, severely swollen joint (possible septic arthritis — emergency) · Joint pain with fever and systemic illness · Rapidly progressing joint erosion · Joint pain after trauma with suspected fracture
A hot, red, swollen joint with fever is a medical emergency until septic arthritis is excluded. Attend A&E the same day — do not wait for a GP appointment.
What Causes Joint Pain?
Joint pain has many possible causes ranging from acute injury to chronic degenerative or inflammatory disease. Getting the correct diagnosis is crucial as treatments differ fundamentally.
Osteoarthritis (OA) causes progressive loss of articular cartilage, subchondral bone remodelling, and osteophyte formation. It is the most common cause of chronic joint pain in adults over 50, affecting knees, hips, hands, and spine.
Rheumatoid arthritis (RA) is a systemic autoimmune disease in which the immune system attacks synovial joints, causing chronic synovitis, joint erosion, deformity, and systemic inflammation. Anti-CCP antibodies are highly specific.
Septic arthritis is a medical emergency caused by bacterial infection of a joint (most commonly Staph aureus). It causes rapid joint destruction and can be fatal. A hot, red, swollen joint with fever always requires emergency joint aspiration.
Non-specific low back pain (no identifiable cause) accounts for 85% of presentations. Disc herniation, facet joint degeneration, and muscle/ligament strain are the most common structural causes. Poor posture and sedentary lifestyle are key contributors.
Osteoarthritis of the lumbar spine causes facet joint degeneration and osteophyte formation, narrowing the spinal canal (spinal stenosis). This causes neurogenic claudication — pain in both legs on walking that improves with bending forward.
Cauda equina syndrome occurs when a large central disc herniation compresses the cauda equina nerve roots, causing bladder/bowel dysfunction, bilateral leg weakness, and saddle anaesthesia. This is a surgical emergency requiring same-day MRI and decompression.
Key Risk Factors
How Is Joint Pain Diagnosed?
Investigation depends on the pattern of joint involvement, associated features, and clinical examination. Blood tests distinguish inflammatory from non-inflammatory causes. Joint aspiration is the key investigation for a hot, swollen joint.
How Is Joint Pain Treated?
Treatment depends on the specific diagnosis. NSAIDs and physiotherapy for OA; DMARDs for RA; colchicine and allopurinol for gout; antibiotics for septic arthritis.
Supportive Measures
Hot and cold therapy, appropriate exercise (low-impact swimming, cycling), weight management, and supportive devices (knee sleeves, walking aids) all help manage joint pain. Pacing activity and avoiding extremes of overloading and inactivity is important in chronic joint pain.
When Joint Pain Becomes Chronic
Chronic joint pain that is not controlled by standard management warrants specialist review. For OA, joint replacement surgery is highly effective when conservative measures fail. For RA, dose adjustment or biologic DMARD initiation is appropriate when disease is not controlled.
When Should You Seek Medical Advice for Joint Pain?
Hot, red, swollen joint with fever (possible septic arthritis) — attend A&E immediately for joint aspiration and IV antibiotics. Delay causes irreversible joint destruction.
Hot, red, swollen joint with fever · New joint pain with morning stiffness >1 hour · Sudden joint pain after injury · Multiple swollen joints with systemic symptoms · Joint pain not responding to analgesia after 2 weeks.
How to Protect Your Joint Health
Joint pain prevention depends on the underlying cause. For OA, weight management and exercise are most effective. For inflammatory arthritis, early treatment is the best prevention of disability.
Weight management reduces load on weight-bearing joints. Every 1kg of body weight loss reduces knee joint loading by 4kg. Low-impact exercise (swimming, cycling) maintains fitness without joint stress.
Physiotherapy-led exercise is more effective than rest for most MSK conditions. Strengthening exercises for the muscles around affected joints reduce pain and improve function. Ask for a referral or self-refer where available.
Warm up adequately before exercise and cool down after. Increase training load gradually (the 10% rule). Strengthen muscles around vulnerable joints (glutes for knee, rotator cuff for shoulder, core for back) to reduce injury risk.
Begin DMARD treatment as early as possible after an RA diagnosis. Early treatment (within 3 months of symptom onset) dramatically reduces joint erosion, disability, and long-term organ damage.
People with inflammatory arthritis (RA, psoriatic, AS) have higher cardiovascular risk. Regular blood pressure, cholesterol, and weight monitoring is recommended. Exercise and smoking cessation are particularly important.
Supportive footwear with good arch support and cushioning is the most important non-pharmacological treatment for plantar fasciitis. Avoid walking barefoot on hard floors, especially in the morning. Replace sports shoes every 500 miles.
Speak to a Clinician About Joint Pain
Through The GP Service, a licensed clinician can assess your joint pain, arrange appropriate blood tests and imaging, and provide onward referral to rheumatology or orthopaedics where needed.



Expert clinical advice, when you need it.
Joint Pain FAQs
Joint pain with a hot, red, severely swollen joint and fever is a red flag for septic arthritis — a surgical emergency. This requires same-day joint aspiration and IV antibiotics. Joint pain without these features requires investigation to determine the cause: OA, RA, gout, or reactive arthritis. Getting the right diagnosis quickly matters because RA causes joint erosion within weeks to months of onset, and early DMARD treatment dramatically reduces long-term disability.
OA affects cartilage and causes pain that worsens with use and eases with rest. RA is an autoimmune disease causing symmetrical synovial inflammation, morning stiffness >1 hour, systemic symptoms, and elevated inflammatory markers. RA gets worse without treatment and causes irreversible joint destruction; OA does not have systemic consequences. Getting the right diagnosis early is important because the treatments are completely different. If you have morning stiffness lasting over an hour and symmetrical joint swelling, see a clinician urgently for RA screening.
Most back pain is non-specific — caused by muscle, ligament, or disc strain without any serious underlying cause. The vast majority resolves within 4–6 weeks. Key red flags to watch for: bladder or bowel changes (possible cauda equina syndrome — call 999), fever, unexplained weight loss, or pain that is unrelenting at night regardless of position. If none of these are present, staying active, taking regular analgesia, and seeing a physiotherapist is the most effective approach.
Bed rest is not recommended and actually slows recovery. Staying as active as pain allows — walking, gentle stretching, swimming — helps the back heal faster. Most non-specific back pain improves within 4–6 weeks with movement, NSAIDs, and physiotherapy. Seeing a physiotherapist early produces better outcomes than waiting. If back pain has not improved after 6 weeks, or is worsening, a GP review is warranted to consider imaging and further management.
Sciatica is caused by compression of the sciatic nerve or its nerve roots — most commonly from a disc herniation at L4/5 or L5/S1. Around 80–90% of sciatica resolves within 6–12 weeks with conservative management: staying active, NSAIDs, physiotherapy, and nerve pain medication if needed. Red flags requiring emergency assessment: loss of bladder or bowel control, saddle numbness, or rapidly progressive leg weakness. These could indicate cauda equina syndrome, which is a surgical emergency.
Gout attacks are caused by a sudden deposition of uric acid crystals in the joint. They are excruciatingly painful, typically beginning at night, affecting the big toe, ankle, or knee. Most attacks settle within 7–14 days. Short-term treatment with NSAIDs, colchicine, or prednisolone brings rapid relief. Urate-lowering therapy with allopurinol prevents recurrent attacks and is very effective. Gout is entirely manageable — it is not something that has to be simply endured.
Allopurinol should never be started during an acute gout attack as this can prolong or worsen the flare. It should be started 2–4 weeks after the acute attack has settled, ideally while continuing prophylactic colchicine or NSAID cover for the first 3–6 months. Start at 100mg daily and increase every 4 weeks to achieve a target serum urate below 360 μmol/L. Once on a stable dose, allopurinol is continued indefinitely. Stopping and restarting is a common cause of recurrent attacks.
Most ankle sprains heal within 6–8 weeks. Grade 1 (stretching) and Grade 2 (partial tear) injuries resolve with physiotherapy and graded return to sport. Grade 3 (complete ligament rupture) may require immobilisation or, rarely, surgery. Proprioception training is essential to prevent recurrence — recurrent ankle sprains dramatically increase long-term instability and OA risk. If you cannot weight bear after an ankle injury, apply the Ottawa rules: inability to weight bear plus bony tenderness at the malleolus warrants an X-ray to exclude fracture.
